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KMID : 1001920030340010065
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Journal of Korean Neurosurgical Society
2003 Volume.34 No. 1 p.65 ~ p.67
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Lymphocytic Hypophysitis
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Cho Chun-Sung
Park Bong-Jin
Kim Young-Joon
Cho Maeng-Ki
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Abstract
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The authors report two cases of lymphocytic hypophsitis: a 38-year-old male patient with headache and diabetes insipidus and in a 6.4-year-old female patient with headache. Magnetic resonance(MR) image of the patients showed mass-like lesions in the hypophysis as well as loss of high signal on T1-weighted MR images. There was evidence of hypopituitarism. Both patients underwent transsphenoidal approaches for histological diagnosis, which was compatable with lymphocytic hypophysitis. When MR image reveals a characteristic pituitary in the hypophysis lesion with relevant clinical symptoms in a patient, one should include "lymphocytic hypophysitis" as one of the diagnostic possibilities, since the therapeutic options are different from those of pituitary tumors.
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KEYWORD
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Lymphocytic hypophysitis, Central diabetes insipidus, Neurohypophysis, Sellar MRI, Transsphenoidal approach
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